2025, Vol. 6, Issue 2, Part E
Cultivation of Cordyceps militaris on food grains under solid-state fermentation for enhancing its biological efficiency
Author(s): A Vimala Rodhe, C Persis Paul and B Sireesha
Abstract: Cordyceps militaris is an Ascomycetes fungus, it can be found on soil-dwelling larvae and pupae. Cordyceps militaris produces cordycepin (3′-deoxyadenosine), a nucleoside analog, and has a broad spectrum of activity showing immunological regulation, anti-cancer, anti-fungal, anti-leukemia and anti-hyper lipidemia activities. In the present study, Cordyceps militaris obtained from the Indian council of agriculture research-Directorate of Mushroom Research, solan, Himachal Pradesh, India. The culture was maintained on Potato Dextrose Agar slants. Addition of grain substrate to the basal media to improve the growth of C. militaris in solid state fermentation was studied. Increase in the biological efficiency of fruiting bodies, mycelium and fermented substrate were observed and concentration of cordycepin was estimated. Among the three grains used in this study, brown rice emerged as the most effective substrate for maximizing both biomass formation and metabolite accumulation of 55% and 12.2 mg/g respectively.
DOI: 10.22271/micro.2025.v6.i2e.289
Pages: 435-440 | Views: 200 | Downloads: 90
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How to cite this article:
A Vimala Rodhe, C Persis Paul, B Sireesha. Cultivation of Cordyceps militaris on food grains under solid-state fermentation for enhancing its biological efficiency. J Adv Microbiol Res 2025;6(2):435-440. DOI: 10.22271/micro.2025.v6.i2e.289
