2025, Vol. 6, Issue 2, Part D
Canine transmissible venereal tumor: An overview
Author(s): Desai Raj V, Khatri Shweta P, Patel Jaynil M and Nakhashi HC
Abstract: Canine Transmissible Venereal Tumor (CTVT) is a contagious neoplasm originating from reticuloendothelial cells, primarily affecting the reproductive tract of dogs. The tumor is transmitted through the direct transfer of viable tumor cells from one dog to another, typically during mating, or through sniffing and licking of affected areas. Metastasis in CTVT is uncommon. Dogs of any breed, age, or sex may be affected, although the condition is most frequently observed in dogs between 2 to 5 years of age, with females showing a slightly higher incidence. In bitches, the tumor commonly develops on the posterior vaginal wall and the vaginal vestibule. Macroscopically, the lesion appears as solitary or multiple masses exhibiting a cauliflower-like surface, ulceration, haemorrhage, and variable size. Diagnosis is based on macroscopic examination, cytology, and histopathology. Additional diagnostic tools such as cytogenetic analysis and hemato-biochemical evaluations may also be utilized. Treatment options for CTVT include chemotherapy (most commonly vincristine), immunotherapy, radiotherapy, excisional surgery, and biotherapy. Among these, chemotherapy is considered the most effective and widely practiced modality.
DOI: 10.22271/micro.2025.v6.i2d.277
Pages: 356-360 | Views: 72 | Downloads: 33
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How to cite this article:
Desai Raj V, Khatri Shweta P, Patel Jaynil M, Nakhashi HC. Canine transmissible venereal tumor: An overview. J Adv Microbiol Res 2025;6(2):356-360. DOI: 10.22271/micro.2025.v6.i2d.277
