2025, Vol. 6, Issue 2, Part D
Nutritional and therapeutic applications of synbiotics in the management of lifestyle disorders: An overview
Author(s): D Jasmine Priya, Paromita Mukherjee, Swati Nakhale and Souvik Tewari
Abstract: Lifestyle disorders such as obesity, type 2 diabetes mellitus, cardiovascular disease, and metabolic syndrome have become major global health challenges due to sedentary behavior, poor dietary patterns, and stress. Recent advances in microbiome science have revealed the pivotal role of gut microbial composition in regulating metabolism, immunity, and inflammation key factors underlying these disorders. Synbiotics, defined as synergistic combinations of probiotics and prebiotics, have gained increasing attention as functional food components that modulate the gut microbiota and confer health benefits. This review highlights the nutritional and therapeutic potential of synbiotics in preventing and managing lifestyle disorders through mechanisms such as modulation of intestinal microbiota, enhancement of gut barrier integrity, reduction of systemic inflammation, and improvement in lipid and glucose metabolism. Clinical evidence supporting the efficacy of synbiotics in obesity, diabetes, dyslipidemia, and non-alcoholic fatty liver disease is summarized, along with future prospects and challenges for their inclusion in functional foods and dietary interventions.
DOI: 10.22271/micro.2025.v6.i2d.273
Pages: 341-347 | Views: 88 | Downloads: 31
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How to cite this article:
D Jasmine Priya, Paromita Mukherjee, Swati Nakhale, Souvik Tewari. Nutritional and therapeutic applications of synbiotics in the management of lifestyle disorders: An overview. J Adv Microbiol Res 2025;6(2):341-347. DOI: 10.22271/micro.2025.v6.i2d.273
