2025, Vol. 6, Issue 1, Part D
Exploring prokaryotic genomes: An analysis of genetic diversity, evolutionary patterns, and functional genomics
Author(s): Rupsa Hazra Chowdhury, Rojina Khatun, Sudeshna Sengupta and Malavika Bhattacharya
Abstract: Prokaryotic genomes are very diverse and flexible due to their compact size and lack of membrane-bound organelles. The analysis of these genomes gives crucial information on microorganisms' physiology, evolution, and ecological functions. Vivid knowledge of prokaryotic genomic organization is completely revolutionized by the development of sequencing technology, which has resulted in an enormous range of genome sizes, gene content, and organization. By Computing core and auxiliary genes, comparative genomics unveils proper adaptability along with their essential functions. Protein interactions & Gene expression are learned by genomic functional tools, i.e., transcriptomics and proteomics. These show the exact response of prokaryotes to environmental inputs. By direct sequencing of DNA from environmental samples without the need for culture, metagenomics enables one to study microbial communities. Bioinformatics software facilitates Large-scale genomic data calculation, which helps in comparative analysis and gene prediction annotation. These studies point out the processes that shape bacterial evolution, including horizontal gene transfer events, mobile genomic elements, and CRISPR-Cas systems. As a result, the identification of prokaryotic genomes provides a pioneer for the understanding of microbial life, and it impacts various ecosystems and human health.
Pages: 278-286 | Views: 85 | Downloads: 40
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How to cite this article:
Rupsa Hazra Chowdhury, Rojina Khatun, Sudeshna Sengupta, Malavika Bhattacharya. Exploring prokaryotic genomes: An analysis of genetic diversity, evolutionary patterns, and functional genomics. J Adv Microbiol Res 2025;6(1):278-286.
