2025, Vol. 6, Issue 1, Part C
Demographic patterns and clinical impact of nosocomial pseudomonas and Acinetobacter infections in Yenagoa hospitals: Evidence for targeted infection control
Author(s): Oyindiepreye Lydia Omu, Easter Godwin Nwokah and Samuel Douglas Abbey
Abstract: Rationale: Nosocomial infections remain a significant source of morbidity andrnmortality in healthcare settings, exacerbated by the rise inrnmultidrug-resistant pathogens. This study was conducted to analyze therndemographic characteristics, types of clinical specimens, and pathogenrnprevalence among hospitalized patients in Yenagoa, providing data to informrntargeted infection control strategies. Objectives: The primary objectives is to examine the demographic patterns andrnclinical Impact of Nosocomial Pathogens with a focus on Pseudomonas, andrnAcinetobacter for targeted infection control. Methods: A total of 200 non-lactose fermenting gram negative isolates sampledrnfrom three healthcare facilities in Yenagoa were included. Demographic datarnwere collected, and Phenotypic identification and antimicrobial sensitivityrntesting of bacterial isolates were conducted to determine the prevalence,rndistribution of pathogens and their susceptibility profiles. Data were analyzedrnto identify the most common pathogens and their association with demographicrnvariables and specimen types. Results: The study population consisted of 60.5% males and 39.5% females, withrnmiddle-aged adults (31-40 years) representing the largest age group (32%).rnWound swabs and urine samples were the predominant clinical sources,rnconstituting 44% and 30% of samples, respectively. Pseudomonas spp. wasrnthe most prevalent pathogen, accounting for 22% of isolates, followed by Proteusrnand Alcaligenes at 19% each. Acinetobacter spp. had a prevalencernof 16.5%, raising concerns due to its multidrug resistance, particularly inrnhigh-risk wards like the ICU. The distribution of pathogens highlighted therndiversity of Gram-negative bacteria contributing to nosocomial infectionsrnacross different wards. The Pseudomonas, and Acinetobacter isolatesrnshowed excellent sensitivity to imipenem at (93.2%) and (97%) respectively,rncompared to all other antimicrobials tested, with cefalexin, cefuroxime,rngentamycin, and even the reserved antibiotics in the study area such asrnertapenem being some of the least sensitive antibiotics. Conclusion: This study underscores the prevalence of nosocomial pathogens inrnhospital settings, with a high representation of multidrug-resistant organisms,rnparticularly in critical care units. The findings suggest that infectionrncontrol measures should be directed towards high-risk areas and patientrndemographics, with a focus on pathogen-specific interventions to mitigate thernspread of resistant bacteria. Recommendation: Healthcare facilities should implement enhancedrninfection control protocols, including targeted surveillance in high-prevalencernareas such as ICUs and surgical wards, and emphasize antimicrobial stewardshiprnto manage multidrug-resistant pathogens.
DOI: 10.22271/micro.2025.v6.i1c.219
Pages: 220-227 | Views: 52 | Downloads: 27
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How to cite this article:
Oyindiepreye Lydia Omu, Easter Godwin Nwokah, Samuel Douglas Abbey. Demographic patterns and clinical impact of nosocomial pseudomonas and Acinetobacter infections in Yenagoa hospitals: Evidence for targeted infection control. J Adv Microbiol Res 2025;6(1):220-227. DOI: 10.22271/micro.2025.v6.i1c.219
