2024, Vol. 5, Issue 2, Part D
Biosynthesized silver nanoparticles from Colpomenia peregrina: A novel approach to combat bacterial infections
Author(s): Vishnu Kiran Manam
Abstract: The rapid emergence of antibiotic-resistant bacteria necessitates innovative approaches to combat bacterial infections. This study explores the biosynthesis of silver nanoparticles (AgNPs) using the marine brown alga Colpomenia peregrina as a cost-effective and eco-friendly method. The aqueous extract of C. peregrina was employed as a reducing and stabilizing agent for synthesizing AgNPs. Characterization of the nanoparticles was performed using UV-Vis spectroscopy, Fourier-transform infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), and X-ray diffraction (XRD) to confirm their formation, size, shape, and crystalline nature. The synthesized AgNPs exhibited potent antibacterial activity against Gram-positive and Gram-negative bacterial strains, as determined by the Kirby Bauer disc diffusion method. The antibacterial mechanism was attributed to the disruption of bacterial cell walls, reactive oxygen species (ROS) generation, and interference with intracellular processes. This study highlights the potential of C. peregrina-mediated AgNPs as a novel antibacterial agent, paving the way for sustainable nanotechnology-based solutions in the fight against bacterial infections. These findings provide a promising foundation for developing alternative antimicrobial therapies and applications in healthcare.
DOI: 10.22271/micro.2024.v5.i2d.188
Pages: 284-289 | Views: 74 | Downloads: 19
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How to cite this article:
Vishnu Kiran Manam. Biosynthesized silver nanoparticles from Colpomenia peregrina: A novel approach to combat bacterial infections. J Adv Microbiol Res 2024;5(2):284-289. DOI: 10.22271/micro.2024.v5.i2d.188
