2024, Vol. 5, Issue 2, Part A
Evaluation of the antibacterial effect of a combination of the ethanolic extracts of Citrus limon peelsand Eucalyptus globulus leaves against Streptococcus pneumoniae
Author(s): Brenda NAMUTEBI, Sarad Pawar Naik BUKKE, Nabona Jackim, Kabali Moses, BUYINZA Nicholas, Narayana GORUNTLA and GR Neel
Abstract: Pneumococcus, also known as Streptococcus pneumoniae, is the cause of several serious human illnesses, including pneumonia, bronchitis, bacterial meningitis, sepsis, otitis media, and corneal ulcers. Some of these illnesses cause morbidity and mortality globally. Streptococcus pneumoniae is currently responsible for most of pneumonia infections globally. ith prevalence ranging from 15% to 53.7%. This study therefore, evaluated the antibacterial activity of a combination of Citrus limon peels and Eucalyptus globulus leaves against Streptococcus pneumoniae. The combined extracts exhibited a moderate antibacterial activity against Streptococcus pneumoniae, which was determined by agar well diffusion method. The combination however exhibited a higher mean and standard error of the mean zone of inhibition 41±2 mm, 35±0.5773 mm, 21±1.5275 mm, compared to the single extracts, even when it contained only half of the concentration of each extract. The MIC of the combination of the extracts of Citrus limon peels and Eucalyptus globulus leaves extracts was 0.488mg/ml, Citrus limon was 1.953 mg/ml and was 1.953 mg/ml. This study revealed no bactericidal action of the extract against the test organism (Streptococcus pneumoniae). The FIC of the extract was 0.4998 which was less than FIC index which is 0.5, this indicated that there was synergistic antibacterial effect of the extract combination.
Pages: 50-57 | Views: 115 | Downloads: 73
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How to cite this article:
Brenda NAMUTEBI, Sarad Pawar Naik BUKKE, Nabona Jackim, Kabali Moses, BUYINZA Nicholas, Narayana GORUNTLA, GR Neel. Evaluation of the antibacterial effect of a combination of the ethanolic extracts of Citrus limon peelsand Eucalyptus globulus leaves against Streptococcus pneumoniae. J Adv Microbiol Res 2024;5(2):50-57.