2024, Vol. 5, Issue 1, Part C
The effect of fungal infection on eye disease by aspergillus endophthalmitis: A review article
Author(s): Sourabh Sharma, Dr. Dinesh Kumar Sharma and Dr. Dilshad Ali
Abstract: Aspergillus fungal endophthalmitis is a rare but severe intraocular infection that can result in significant visual impairment or blindness if not promptly diagnosed and treated. This review provides a comprehensive overview of the pathogenesis, clinical presentation, diagnostic methods, and treatment strategies for Aspergillus endophthalmitis. The infection typically occurs in immunocompromised individuals or following ocular trauma and surgery, presenting with symptoms such as pain, redness, and decreased visual acuity. Diagnosis is challenging due to nonspecific clinical features, necessitating the use of direct microscopy, culture, and molecular techniques like polymerase chain reaction (PCR) for accurate identification. Imaging modalities, including ultrasound B-scan and optical coherence tomography (OCT), are critical for assessing the extent of intraocular involvement. Treatment involves a combination of systemic and intravitreal antifungal therapies, with voriconazole and amphotericin B being the primary agents used. Surgical interventions, such as pars plana vitrectomy, are often required to manage the infection effectively. Despite advances in diagnostic and therapeutic approaches, the prognosis for Aspergillus endophthalmitis remains guarded, highlighting the need for early detection and aggressive management. This review underscores the importance of multidisciplinary collaboration in improving patient outcomes and advancing the understanding of this complex condition.
Pages: 233-236 | Views: 319 | Downloads: 175
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How to cite this article:
Sourabh Sharma, Dr. Dinesh Kumar Sharma, Dr. Dilshad Ali. The effect of fungal infection on eye disease by aspergillus endophthalmitis: A review article. J Adv Microbiol Res 2024;5(1):233-236.