2024, Vol. 5, Issue 1, Part B
A comprehensive review on production of polyhydroxybutyrate (PHB)
Author(s): Kaushal Radadiya and Trupti Pandya
Abstract: Polyhydroxybutyrate (PHB) stands out as a biocompatible and biodegradable thermoplastic polymer produced by specific bacterial strains. This comprehensive review explores the production of PHB, highlighting its potential applications and challenges. Various microbial sources capable of synthesizing PHB, including bacteria, cyanobacteria, and yeasts, are discussed alongside their optimal growth conditions and substrate preferences. Additionally, genetic engineering approaches for enhancing PHB production in bacteria, particularly Escherichia coli, are examined. Fermentation methods for PHB production, such as batch culture and fed-batch systems, are evaluated, emphasizing the need for precise environmental control. Despite the promising outlook for bioplastics from bacterial sources, challenges remain in strain selection, genetic manipulation, and scaling up production processes. Addressing these challenges will be crucial for realizing the full potential of PHB as a sustainable alternative to traditional plastics.
Pages: 136-142 | Views: 1806 | Downloads: 1356
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How to cite this article:
Kaushal Radadiya, Trupti Pandya. A comprehensive review on production of polyhydroxybutyrate (PHB). J Adv Microbiol Res 2024;5(1):136-142.
