2023, Vol. 4, Issue 2, Part B
Frequencies and phenotypes of antibiotic resistance in non-fermentating bacteria isolated at the China-Guinea Friendship Hospital of Kipé in Conakry, Guinea
Author(s): Abdoulaye Makanéra, Taliby Dos Camara, Koi Koivogui, Mariam Condé, Falila Moussa Adamou, Mamadou Alpha Diallo, Daouda Camara, Tiguidanké Diakité, Alpha Oumar Barry and Mariama Condé
Abstract: Introduction: Multidrug-resistant bacterial infections constitute a major global public health problem, particularly in developing countries. Objective: To determine the diversity and antibiotic resistance phenotypes of non-fermentative Gram negative bacilli (NFGNB) isolated at the China-Guinea Friendship Hospital (HASIGUI). Methodology: This is a nine-month prospective study, carried out in patients at the HASIGUI Biomedical Laboratory from May 1, 2019 to February 1, 2020. Bacterial identification and antibiogram were carried out using a machine. Vitek 2 Compact. Results: A total of 86 NFGNB strains isolated from different biological fluids were analyzed. The average age of the patients was 45.08 years with the range from 1 year to 98 years. The female gender was dominant with 59.30%. The sex ratio (M/F) was 0.6. Fourteen NFGNB species belonging to seven bacterial genera were identified. Sphingomonas paucimobilis was the predominant species (33.72%), followed by Acinetobacter baumanni complex (22.10%), Pseudomonas aeruginosa and Pseudomonas fluorescens each representing 10.46%. Cases of multi-resistance were observed in all families of antibiotics tested. Resistance was common in some antibiotics: oxacillin (100%), ampicillin (62%), norfloxacin (66%), nalidixic acid (66%), cotrimoxazole (59.42%), cefoxitin (50%), and cefuroxime (50%). On the other hand, the most active antibiotics on BGNnf were: vignecycline (100%), imipenem (97.23%), meropenem (88.24%), minocycline (85%), piperacillin-tazobactam (83.87%), amikacin (93.87%), gentamicin (84%), tobramycin (81.43%), levofloxacin (64.28%), ofloxacin (61.70%), ciprofloxacin (60%). Conclusion: Antibiotic resistance phenotypes of BGNnf indicate the need for antibiotic therapy based on antibiogram results.
DOI: 10.22271/micro.2023.v4.i2b.120
Pages: 158-164 | Views: 187 | Downloads: 70
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How to cite this article:
Abdoulaye Makanéra, Taliby Dos Camara, Koi Koivogui, Mariam Condé, Falila Moussa Adamou, Mamadou Alpha Diallo, Daouda Camara, Tiguidanké Diakité, Alpha Oumar Barry, Mariama Condé. Frequencies and phenotypes of antibiotic resistance in non-fermentating bacteria isolated at the China-Guinea Friendship Hospital of Kipé in Conakry, Guinea. J Adv Microbiol Res 2023;4(2):158-164. DOI: 10.22271/micro.2023.v4.i2b.120
