Journal of Advances in Microbiology Research
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P-ISSN: 2709-9431, E-ISSN: 2709-944X

2023, Vol. 4, Issue 1, Part B


Examine the impact of chemical therapies on the biochemical parameters of cancer patients in Thi-Qar Governorate


Author(s): Ghada Mgeed Lafa and Dr. Mohannad Abdulrazzaq Gati

Abstract: This research aimed to investigate chemotherapy's influence on the biochemical alterations of cancer patients in Thi-Qar Governorate. The study comprised 138 volunteers and 46 breast cancer patients divided into 23 samples collected (1-5 doses) and 23 samples taken more than 5 doses. 46 healthy people, 23 men, and 23 women. Paclitaxel and carboplatin were used in the therapy, and 46 males with liver cancer were divided into 23 samples taken (1-5 doses) and 23 samples taken more than 5 doses. Doxorubicin was used as a therapy. The research was carried out at Al-Haboubi Hospital's Department of Oncology. The liver enzymes. We notice changes and an increase in these enzymes when taking chemotherapy. There is a significant difference between the group that took (1_5 dose) and the group that took more than five doses. For females with breast cancer, males notice an increase in liver enzymes, and we notice a difference significant in ALT. As for lipids, it is noted that there are evident changes, an increase in cholesterol and TG, and a decrease in HDL, and there is no significant difference between the females who took (1-5 doses) and the group that took more than 5 doses, As for males, we notice an increase in cholesterol, LDL, TG, and a decrease in HDL. For males, we notice a clear decrease in testosterone and FSH of the hormones compared to o the normal level. For the hormones E2 and LH, we notice a clear decrease in the value of the hormones compared to o the normal level.

Pages: 134-138 | Views: 425 | Downloads: 202

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Journal of Advances in Microbiology Research
How to cite this article:
Ghada Mgeed Lafa, Dr. Mohannad Abdulrazzaq Gati. Examine the impact of chemical therapies on the biochemical parameters of cancer patients in Thi-Qar Governorate. J Adv Microbiol Res 2023;4(1):134-138.
Journal of Advances in Microbiology Research
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