2022, Vol. 3, Issue 2, Part A
Glanders: A highly infectious re-emerging serious zoonotic bacterial disease
Author(s): Dr. Mahendra Pal, Kirubel Paulos Gutama, Nugusa Desalegn Gerbaba, Margo Yonas Shuramo and Fikiru Shifera
Abstract: Glanders is a highly infectious re-emerging zoonotic disease that produces serious disease in humans and animals, especially equines. The disease is caused by Burkholderia mallei, a gram-negative, facultative intracellular pathogen. It is mostly an equine disease that affects horses chronically and donkeys and mules acutely. Humans are affected when contacted with infected animals or contaminated environments. The disease is endemic in developing continents like Africa, Asia, and South America. By testing, destroying positive animals, and limiting the import of animals from foreign nations, the disease has been eradicated from many countries. However, it is seen when re-emerged in many parts of world. The bacteria cause nodules and ulcerations in the upper respiratory tract and lungs.Though Burkholderia mallei is susceptible to various antibiotics but it is difficult for early diagnosis.Early diagnosis and treatments are crucial. The gold standard approach for diagnosing glanders is the isolation and identification of B. mallei from clinical samples. Animal field diagnosis frequently involves the mallein test. Glanders has been identified as a biological threat agent of category "B" and is capable of being utilized as a biological weapon. Neither human nor veterinary vaccination is available in Glanders. As a result, it's crucial to adopt preventative measures, particularly by farmers, equine handlers, veterinarians, and anybody else who might be at danger. It's also necessary to raise knowledge of how to avoid and control it in endemic areas.
Pages: 25-28 | Views: 422 | Downloads: 187
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How to cite this article:
Dr. Mahendra Pal, Kirubel Paulos Gutama, Nugusa Desalegn Gerbaba, Margo Yonas Shuramo, Fikiru Shifera. Glanders: A highly infectious re-emerging serious zoonotic bacterial disease. J Adv Microbiol Res 2022;3(2):25-28.