2020, Vol. 1, Issue 2, Part A
Pathogenesis and Immunology of Chromoblastomycosis: A review
Author(s): Ezemba Chinyere C, Anyaogu Ebuka V, Etikudike Victor O, Osuala Oluchi J, Ezemba, Arinze S and Madukwe Chiamaka J
Abstract: Chromoblastomycosis (CBM), commonly known as chromo mycosis. It is regarded as the most popular mycoses which is caused by melodized or brown-pigmented fungi, and a popular implantation fungal infections. It's a chronic skin and subcutaneous tissue infection caused by a fungus. A traumatic injury and the inoculation of microorganisms from a specific group of Dematiaceous fungi are the most common causes of infection (usually Fonsecaea pedrosoi, Phialophora verrucosa, Cladophialophora carrionii). Lesions of chromoblastomycosis can be veracious, nodular, tumoral, plaque-like, or atrophic. It can be said to be common in tropical and subtropical areas, although there have been a few cases reported in temperate areas as well. The condition primarily affects current or past farm laborers, primarily men, and frequently has crippling consequences. CBM can lead to inability to labor due to fibrotic sequelae and a slew of clinical problems, and if not caught early enough, the condition can be resistant to antifungal treatment. Direct examination, culture, and histopathology are used as diagnostic procedures. Despite a number of therapeutic options, including extensive courses of antifungals, surgical excision, and damaging physical therapy, the disease remains one of the most difficult to eradicate deep mycotic infections. This review seeks to elaborately discuss the pathogenesis and immunological response to Chromoblastomycosis.
Pages: 61-66 | Views: 120 | Downloads: 59
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How to cite this article:
Ezemba Chinyere C, Anyaogu Ebuka V, Etikudike Victor O, Osuala Oluchi J, Ezemba, Arinze S, Madukwe Chiamaka J. Pathogenesis and Immunology of Chromoblastomycosis: A review. J Adv Microbiol Res 2020;1(2):61-66.